The great debate: varicocele treatment and impact on fertility

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• 作者：Matthew A. Will ; Jason Swain ; Mikkel Fode ; Jens Sonksen ; Gregory M. Christman ; Dana Ohl
• 关键词：Varicocele ; surgical repair ; male factor infertility ; semen analysis ; pregnancy rates
• 刊名：Fertility and Sterility
• 出版年：2011
• 出版时间：1 March 2011
• 年：2011
• 卷：95
• 期：3
• 页码：841-852
• 全文大小：256 K

文摘

Objective

To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility.

Design

Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations.

Conclusion(s)

Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).