Pathology report assessment of incidental gallbladder carcinoma diagnosed from cholecystectomy specimens: Results of a French multicentre survey

详细信息    查看全文

• 作者：Denis Chatelain ; David Fuks ; Olivier Farges ; Christophe Attencourt ; Fran莽ois Ren茅 Pruvot ; Jean-Marc Regimbeau
• 关键词：Gallbladder carcinoma ; Pathologist ; Pathology report
• 刊名：Digestive and Liver Disease
• 出版年：December, 2013
• 年：2013
• 卷：45
• 期：12
• 页码：1056-1060
• 全文大小：484 K

文摘

Aims

To assess the accuracy of pathology reports on gallbladder specimens from patients operated on for incidental gallbladder carcinoma.

Methods

Demographic data, details on pathological reports including gross and microscopic features section were recorded in 100 selected patients with incidental gallbladder carcinoma diagnosed from 2004 to 2007.

Results

Pathology reports had a conventional format in 93% of cases, without any standardization. Turnaround time ranged from 1 to 35 days. Frozen sections were performed in 20% of cases. The reports failed to give information on prognostic histological factors: exact tumour site (missing in 55% of cases), depth of tumour infiltration within the gallbladder wall (missing in 10%), surgical margins (missing in 40% for the cystic duct margin), tumour differentiation (missing in 28%), vascular invasion (missing in 52%) and perineural invasion (missing in 51%). Lymph node status could be assessed in 44% of cases. Distances between the tumour and the cystic duct and circumferential margins were not specified in 68% and 84% of cases. Only 29% of the reports clearly stated the pTNM stage in the conclusion section. The pT stage with margin status and tumour site was only mentioned in 30% of the reports.

Conclusion

Pathology reports on gallbladder carcinoma from participating centres frequently lacked important information on key prognostic histological factors.