Antisynthethase syndrome presenting as peripheral limb fasciitis

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• 作者：Mikael Ebbo ; Christophe Chagnaud ; Dominique Figarella-Branger ; Stevan Legall ; Jean-Robert Harle ; Nicolas Schleinitz
• 关键词：Antisynthetase syndrome ; Fasciitis ; Dermatomyositis ; Muscle MRI
• 刊名：Joint Bone Spine
• 出版年：2013
• 出版时间：October, 2013
• 年：2013
• 卷：80
• 期：5
• 页码：528-530
• 全文大小：1134 K

文摘

Inflammatory myopathy is a major clinical manifestation of the antisynthetase syndrome. Patients with anti Jo-1 antibodies can also present with other clinical manifestations as arthritis, mechanic's hands and lung fibrosis. As in dermatomyositis, polymyositis and overlap myopathies proximal muscle of the limbs are preferentialy involved. Associated fascia edema on magnetic resonance imagery studies with histological proven fasciitis has been reported. However peripheral limb involvement, reported here in two patients, as the isolated initial manifestation is unusual.