Gold nanoparticles induce apoptosis, endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils
详细信息 查看全文
- 作者：Claudie Noë ; l ; Jean-Christophe Simard ; Denis Girard ; Denis.girard@iaf.inrs.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gold nanoparticles ; Neutrophils ; Apoptosis ; Caspases ; Endoplasmic reticulum ; Cytoskeleton
- 刊名：Toxicology in Vitro
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：31
- 期：Complete
- 页码：12-22
- 全文大小：1837 K
文摘
- •
We examine the interaction between gold nanoparticles and human neutrophils.
- •
Gold nanoparticles induce apoptosis by a caspase dependent mechanism.
- •
Gold nanoparticles are endoplasmic reticulum stressors.
- •
Gold nanoparticles induce cleavage of cytoskeletal proteins.
- •
Gold nanoparticles do not enhance cell surface expression of cytoskeletal proteins.