Guidelines of care for the management of primary cutaneous melanoma

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• 作者：Christopher K.  ; Bichakjian MD^a ; Allan C.  ; Halpern MD (Co-chair)^b ; Timothy M.  ; Johnson MD (Co-chair)^a ; Antoinette  ; Foote Hood MD^c ; James M.  ; Grichnik MD ; PhD^d ; Susan M.  ; Swetter MD^e ;   ; ^f ; Hensin  ; Tsao MD ; PhD^g ; Victoria Holloway  ; Barbosa MD^h ; Tsu-Yi  ; Chuang MD ; MPHⁱ ;   ; ^j ; Madeleine  ; Duvic MD^k ; Vincent C.  ; Ho MD^l ; Arthur J.  ; Sober MD^g ; Karl R.  ; Beutner MD ; PhD^m ;   ; ⁿ ; Reva  ; Bhushan PhD^o ;   ; ^{rbhushan@aad.org} ; Wendy  ; Smith Begolka MS^o
• 关键词：biopsy ; follow-up ; melanoma ; pathology report ; sentinel lymph node biopsy ; surgical margins
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2011
• 出版时间：November 2011
• 年：2011
• 卷：65
• 期：5
• 页码：1032-1047
• 全文大小：197 K

文摘

The incidence of primary cutaneous melanoma has been increasing dramatically for several decades. Melanoma accounts for the majority of skin cancer¨Crelated deaths, but treatment is nearly always curative with early detection of disease. In this update of the guidelines of care, we will discuss the treatment of patients with primary cutaneous melanoma. We will discuss biopsy techniques of a lesion clinically suspicious for melanoma and offer recommendations for the histopathologic interpretation of cutaneous melanoma. We will offer recommendations for the use of laboratory and imaging tests in the initial workup of patients with newly diagnosed melanoma and for follow-up of asymptomatic patients. With regard to?treatment of primary cutaneous melanoma, we will provide recommendations for surgical margins and?briefly discuss nonsurgical treatments. Finally, we will discuss the value and limitations of sentinel lymph node biopsy and offer recommendations for its use in patients with primary cutaneous melanoma.