Expression of bovine non-classical major histocompatibility complex class I proteins in mouse P815 and human K562 cells
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- 作者：Parveen Parasara ; c ; Amanda Wilhelma ; c ; Heloisa M. Rutiglianoa ; b ; Aaron J. Thomasa ; c ; Lihong Tenga ; c ; Bi Shia ; c ; William C. Davisd ; Carlos E. Suareze ; Daniel D. Newd ; 1 ; Kenneth L. Whitea ; b ; c ; Christopher J. Daviesa ; b ; c ; chris.davies@usu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bovine leukocyte antigens (BoLA) ; Human K562 cells ; Major histocompatibility complex ; Mouse P815 cells ; Non-classical MHC class I
- 刊名：Research in Veterinary Science
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：107
- 期：Complete
- 页码：161-170
- 全文大小：1987 K
文摘
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Bovine non-classical MHC-I proteins can be either membrane associated or secreted.
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BoLA-NC1*00501, -NC3*00101 and -NC4*00201 were membrane associated proteins.
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The BoLA-NC1*00401 splice variant was expressed as a secreted protein.
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BoLA-NC2*00102 remained intracellular and may require a specific peptide antigen.