Collection tubes containing citrate stabiliser over-estimate plasma glucose, when compared to other samples undergoing immediate plasma separation

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• 作者：Rebekah Carey^a ; Helen Lunt^b ; ^c ; ^{helen.lunt@cdhb.health.nz} ; Helen F. Heenan^b ; Christopher M.A. Frampton^c ; Christopher M. Florkowski^b ; ^d
• 关键词：Blood glucose ; Glycolysis ; Plasma ; Citrate ; Diagnosis ; laboratory ; Blood chemical analysis ; Bias ; systematic ; Diabetes
• 刊名：Clinical Biochemistry
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：49
• 期：18
• 页码：1406-1411
• 全文大小：530 K
• 卷排序：49

文摘

Terumo™ Venosafe citrate tubes ‘read’ glucose higher (0.37mmol/L) than research grade preparation with lithium heparin tubes When plasma separation is delayed, citrate blood collection tubes stabilise glucose over a wide range of glucose values Pre-analytical glucose loss over 24 hr best fits a model of absolute loss (around 0.2 mmol.L-1.hr-1) rather than % loss