The Baeyer–Villiger oxidation of ketones with Oxone^® in the presence of ionic liquids as solvents

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• 作者：Anna Chrobok
• 关键词：Baeyer– ; Villiger oxidation ; Ionic liquids ; Oxone^® ; ; Lactones ; Esters
• 刊名：Tetrahedron
• 出版年：2010
• 出版时间：7 August 2010
• 年：2010
• 卷：66
• 期：32
• 页码：6212-6216
• 全文大小：563 K

文摘

Cyclic and linear ketones were readily oxidised with Oxone^® at 40 °C in ionic liquids as solvents and short times (2.5–20 h), affording their corresponding lactones and esters in high yields (65–95 % ). Both, aprotic and protic ionic liquids were used. The best conversion of ketones and the highest yields of products were obtained with 1-buty-3-methylimidazolium tetrafluoroborate and 1-methylimidazolium acetate as solvents. These ionic liquids were also efficiently recycled in the Baeyer–Villiger reaction without significant loss of activity. Several factors, such as the partial solubility of KHSO₅ in the ionic liquid, its viscosity and the presence of a proton in protic ionic liquids, have an influence on the course of the reaction.