Therapeutic drug monitoring is a daily practice in clinical laboratories of the Hospitals.

Micellar liquid chromatography is used to perform the monitoring, and the use of this technique has been here reviewed.

The studied groups are: anticonvulsants, antiarrhythmics, tricyclic antidepressants, analgesics and bronchodilators.

Detection techniques includes UV absorbance or amperometry, and samples are serum and urine.

All methods has been optimized and validated.