刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2017
出版时间:5 February 2017
年:2017
卷:134
期:Complete
页码:352-360
全文大小:2759 K
卷排序:134
文摘
SFC was used to separate and isolate two pairs of 7-epimers of SOAs. Acetonitrile stabilized two pairs of epimers and was used as modifier in SFC. Two achiral UPC2 methods were established on the Torus 1-AA and Diol columns. Preparative SFC enabled isolation of four SOA compounds with the purity >95%. SFC provides a solution to preparation of high-purity reference standards.