Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis
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- 作者：Alexandre Grand-Guillaume Perrenouda ; b ; Alexandre.Grand-Guillaume-Perrenoud@rd.nestle.com" class="auth_mail" title="E-mail the corresponding author ; Davy Guillarmea ; Julien Boccarda ; Jean-Luc Veutheya ; Denis Barronb ; Sofia Mocob
- 关键词：UHPSFC-MS ; QqTOF-MS ; Diverse natural compounds ; Natural products extracts ; Bioactive compounds
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：1450
- 期：Complete
- 页码：101-111
- 全文大小：2782 K
文摘
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Evaluation of UHPSFC-QqTOF/MS for plant metabolites analysis and profiling.
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120 diverse natural compounds were tested on 15 different stationary phase chemistries.
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88% of the tested compounds were successfully analyzed in SFC.
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Three stationary phases (Diol, not endcapped C18 and 2-EP) were particularly interesting.
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UHPSFC-QqTOF/MS allows the metabolite profiling of both polar and non-polar plant extracts.