Fast separation of triterpenoid saponins using supercritical fluid chromatography coupled with single quadrupole mass spectrometry
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- 作者：Yang Huanga ; 1 ; Tingting Zhanga ; 1 ; Haibo Zhoua ; Ying Fenga ; Chunlin Fana ; Weijia Chena ; Jacques Crommena ; b ; Zhengjin Jianga ; jzjjackson@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Triterpenoid saponins ; Supercritical fluid chromatography ; Traditional Chinese medicines
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：20 March 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：22-29
- 全文大小：1603 K
文摘
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Rapid and highly efficient SFC-MS methods were developed for the separation of triterpenoid saponins (TSs).
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Water can be considered as a suitable mobile phase additive for SFC-MS operation.
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The SFC-MS method developed for the separation of kudinosides shows higher resolution and shorter running time than LC–MS.
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The SFC-MS approach shows potential for analyzing TSs present in traditional Chinese medicines (TCMs).