Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy
详细信息 查看全文
- 作者：Nai-Ching Chena ; b ; 1 ; Yao-Chung Chuanga ; c ; 1 ; Chi-Wei Huanga ; b ; Chun-Chung Luid ; Chen-Chang Leed ; Shih-Wei Hsud ; Pin-Hsuan Linb ; Yan-Ting Lua ; Ya-Ting Changa ; b ; Che-Wei Hsua ; Chiung-Chih Changa ; neur099@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Interictal epileptiform discharges ; Brain-derived neurotrophic factor ; Diffusion tensor imaging ; Demyelinating ; Corpus callosum
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：147-154
- 全文大小：1068 K
文摘
- •
The temporal lobe epilepsy (TLE) patients may show in cognitive deficits other than the memory domains.
- •
Decreased serum BDNF levels were found at the chronic phase.
- •
BDNF modulate the regional white matter integrity that predicts the cognitive performances in TLE patients.