MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder
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- 作者：Kai-Feng Hunga ; Chung-Ji Liua ; c ; Peng-Chih Chiub ; Jiun-Sheng Lina ; c ; Kuo-Wei Changa ; d ; Wen-Yu Shiha ; d ; Shou-Yen Kaoa ; d ; sykao@vghtpe.gov.tw" class="auth_mail" title="E-mail the corresponding author ; Hsi-Feng Tua ; b ; hftu@ym.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Carcinogenesis ; Malignant ; Marker ; MicroRNA ; miR-31 ; Saliva ; OPMD
- 刊名：Oral Oncology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：53
- 期：Complete
- 页码：42-47
- 全文大小：809 K
文摘
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Increased miR-21, miR-31 are detected in saliva from OPMD cases.
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Among OPMD cases, tissue miR-31 expression could distinguish cases with either recurrence or malignant transformation.
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Dysplasia and miR-31 expression are independent risk factors for predicting either OPMD recurrence or malignant transformation.