The association of carotid intima-media thickness with serum Level of perfluorinated chemicals and endothelium-platelet microparticles in adolescents and young adults
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- 作者：Chien-Yu Lina ; b ; Pau-Chung Chenc ; d ; e ; Shyh-Chyi Lof ; Pao-Ling Torngg ; Fung-Chang Sungh ; Ta-Chen Suc ; i ; tachensu@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author ; tachensu@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：8-OHdG ; 8-hydroxydeoxyguanosine ; BMI ; body mass index ; CIMT ; carotid intima-media thickness ; SBP and DBP ; systolic and diastolic blood pressure ; EMPs ; endothelial microparticles ; hs-CRP ; high sensitivity C-reactive protein ; HDL-C ; high-density lipoprotein cholesterol ; LDL-C ; low-density lipoprotein cholesterol ; HOMA ; homeostasis model assessment of insulin resistance ; NHANES ; National Health and Nutrition Examination Survey ; NTD ; new Taiwan dollar ; PFCs ; perfluorinated chemicals ; PFOA ; perfluoro
- 刊名：Environment International
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：94
- 期：Complete
- 页码：292-299
- 全文大小：477 K
文摘
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The association between CIMT, serum PFCs and microparticles was studied among 848 persons in a young Taiwanese cohort.
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The serum PFOS concentration was positively associated with serum CD31 +/CD42a − and CD31 +/CD42a +.
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The positive association between PFOS and CIMT was more evident when CD31 +/CD42a − and CD31 +/CD42a + were elevated.