Internalization and cytotoxicity effects of carbon-encapsulated iron nanoparticles in murine endothelial cells: Studies on internal dosages due to loaded mass agglomerates
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- 作者：Monika A. Cywinskaa ; Michal Bystrzejewskib ; Magdalena Poplawskac ; Anita Kosmidera ; Robert Zdanowskid ; Slawomir Lewickid ; Zbigniew Fijaleke ; Agnieszka Ostrowskaf ; Magdalena Bamburowicza ; Andrzej Cieszanowskig ; Ireneusz P. Grudzinskia ; ireneusz.grudzinski@wum.edu.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Iron-carbon (core-shell) type hybrid nanoparticles ; Endothelial (HECa-10) cells ; Agglomerates ; Internalization ; Zeta potential ; Cytotoxicity
- 刊名：Toxicology in Vitro
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：34
- 期：Complete
- 页码：229-236
- 全文大小：1567 K
文摘
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Carbon-encapsulated iron nanoparticles (CEINs) loaded as agglomerates in HECa-10.
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CEIN agglomerates enter the endothelial cells through the endocytic pathway.
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CEIN agglomerates affect the Zeta potential of HECa-10 cells.
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CEIN agglomerates induce membrane and mitochondrial cytotoxicities in HECa-10 cells.