Distinct Signaling Roles of cIMP, cCMP, and cUMP

详细信息    查看全文

• 作者：Roland Seifert¹ ; ^{seifert.roland@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Structure
• 出版年：2016
• 出版时间：4 October 2016
• 年：2016
• 卷：24
• 期：10
• 页码：1627-1628
• 全文大小：245 K

文摘

The cyclic purine nucleotide cIMP and the cyclic pyrimidine nucleotides cCMP and cUMP are emerging second messengers. These cNMPs show different biological effects, but the molecular mechanisms remain elusive. In this issue of Structure, Ng et al. (2016) provide structural evidence for distinct interactions of cIMP, cCMP, and cUMP with ion channels.