The radiation dose of volume perfusion computed tomography (VPCT) can be successfully reduced by means of reducing tube voltage to 70 kV and that perfusion-based entire SPN characterization is feasible.
The two calculation methods (maximum slop + Patlak and deconvolution) deliver different absolute values for parameters, such as BF, BV and k-trans, which correlate well for BF and BV.
The perfusion parameters of 70 kV—VPCT can be used to differ the pulmonary lesion from normal tissue.