Sulfated polysaccharide from the marine algae Hypnea musciformis inhibits TNBS-induced intestinal damage in rats
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- 作者：Tarcisio V. Britoa ; Francisco C.N. Barrosb ; e ; Renan O. Silvac ; Genilson J. Dias Jú ; niora ; José ; Simiã ; o C. Jú ; niora ; Á ; lvaro X. Francoc ; Pedro M.G. Soaresc ; d ; Luciano S. Chavesb ; Clara M.W.S. Abreuf ; Regina C.M. de Paulaf ; Marcellus H.L.P. Souzac ; Ana Lú ; cia P. Freitasb ; André ; Luiz R. Barbosaa ; andreluiz@ufpi.edu.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sulfated polysaccharide ; Marine algae ; Colitis ; Inflammatory disease
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 October 2016
- 年：2016
- 卷：151
- 期：Complete
- 页码：957-964
- 全文大小：1757 K
文摘
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Polysaccharides (PLS) significantly reduced the inflammatory response during colitis induced by TNBS.
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PLS reduced the neutrophil migration and decreased the cytokine level on colonic tissue.
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Pre-treatment of rats with PLS significantly reduced the oxidative stress and damage on the intestinal tract.