A simple and rapid detection assay for peptides based on the specific recognition of aptamer and signal amplification of hybridization chain reaction
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- 作者：Chao Maa ; Haiyun Liua ; Tian Tiana ; Xianrang Songb ; Jinghua Yua ; Mei Yana ; chm_yanm@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Peptide ; Aptamer ; Graphene oxide ; Hybrid chain reaction
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 September 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：15-18
- 全文大小：762 K
文摘
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The hybridization chain reaction, which is a enzyme-free amplification reaction,, is simple and low in cost.
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The aptamer can not only identify target peptides, but also initiate the HCR, and the background is greatly reduced due to the quenching effect of GO.
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The novel assay shows great sensitivity in the detection of peptide and has great potential in various peptides and even cells.