Dendronized mesoporous silica nanoparticles for intracellular drug delivery.
Low cytotoxicity with no impact on the metabolism of endothelial cells.
Specific cancer cell targeting due to receptor-mediated cell uptake.
Redox-driven cleavage of disulfide bridges allows stimuli-responsive cargo release.
Endosomal escape based on the high buffering capacity of PAMAM dendrons.