One of the most conspicuous attributes of the canyon-fill sediments exposed at Colle Montarone is their pronounced cyclic packaging, resulting from several pulses of erosion and fill. The lithofacies listed above combine to form a number of discontinuity-bound stratal packages, or high-frequency depositional sequences, each characteristically having an overall fining-upward character. Within sequences, systematic vertical trends in their constituent lithofacies define two main stratigraphic motifs, namely Motif-1 and Motif-2, which are typical of CMC1 and CMC2, respectively. Each sequence is deemed to reflect cyclical changes in volume, composition, and rheology of sediment gravity flows entering the canyons and comprises a basal unconformity (sequence boundary), succeeded by a high net-gross channel-levee complex (lowstand systems tract), overlain by a succession of either a low net-gross heterolithic deposits (early transgressive systems tract, Motif-1 sequences) or mass-transport deposits (transgressive to falling stage systems tract, Motif-2 sequences). Given the severe Icehouse climatic regime during the Pleistocene, the cyclic arrangement is most reasonably attributed primarily to repeated glacio-eustatic fluctuations in global sea level, which regulated the flux of terrigenous clastic sediment to the slope and basin-floor settings. Results from this paper are directly applicable to the oil and gas industry when making predictions of reservoir and seal relationships within slope turbidite systems developed during periods of high-frequency, eustatic sea-level fluctuations.