A rapid synthesis of 2-substituted 1,2,3- triazole-1-oxide derivative starting from 4-(methyl)isonitrosoacetophenone and its Ni(II) complex: Characterization, DNA binding and cleavage properties
文摘
A new 1,2,3-triazole 1-oxide was synthesized through a simple one-pot method. The crystal structure was determined by single-crystal X-ray diffraction method. It was as a chelator for biorelevant NiII ion. DNA binding and cleavage properties of the 1,2,3-triazole 1-oxide and its NiII complex were investigated.