A Critical Appraisal of Control Strategies for Soil-Transmitted Helminths

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• 作者：Suzy J. Campbell¹ ; ^{suzanne.campbell@anu.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Susana V. Nery¹ ; James S. McCarthy² ; ³ ; Darren J. Gray¹ ; ² ; Ricardo J. Soares Magalhã ; es⁴ ; ⁵ ; Archie C.A. Clements¹
• 刊名：Trends in Parasitology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：32
• 期：2
• 页码：97-107
• 全文大小：1889 K

文摘

Interventions that lead to reductions in soil-transmitted helminths (STHs) include chemotherapy with anthelmintic drugs and improvements in water, sanitation, and hygiene (WASH). In this opinion article we aim to determine the evidence for optimal approaches for STH control. First we explore the evidence for the above interventions. We then appraise two integration strategies: current chemotherapy-oriented integrated neglected tropical disease (NTD) control and expanded ‘multicomponent integration’, which includes integrated chemotherapy, WASH, and other intervention strategies. While multicomponent integrated control may be an effective approach to sustainably reduce STH transmission, there is a need for evidence to prove the feasibility of this approach.