Identifying clinical measures that most accurately reflect the progression of disability in Parkinson disease
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- 作者：Terry D. Ellisa ; tellis@bu.edu" class="auth_mail" title="E-mail the corresponding author ; James T. Cavanaughb ; Gammon M. Earhartc ; Matthew P. Fordd ; K. Bo Foremane ; Anne Thackeraye ; Matthew S. Thiesef ; Leland E. Dibblee
- 关键词：Parkinson disease ; Natural history ; Disability ; Progression
- 刊名：Parkinsonism & Related Disorders
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：25
- 期：Complete
- 页码：65-71
- 全文大小：470 K
文摘
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Various dimensions of disability declined at distinct rates over 2-years in PD.
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The steepest declines occurred in gait, gait-related balance and motor impairments over a 2-year period.
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Declines in gait speed and gait-related balance are important markers of disability.
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Early treatment to reduce gait related disability in PD is warranted.