Dataset of mRNA levels for dopaminergic receptors, adrenoceptors and tyrosine hydroxylase in lymphocytes from subjects with clinically isolated syndromes

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• 作者：Marco Cosentino^a ; ^{marco.cosentino@uninsubria.it} ; Mauro Zaffaroni^b ; Massimiliano Legnaro^a ; Raffaella Bombelli^a ; Laura Schembri^a ; Damiano Baroncini^b ; Anna Bianchi^b ; Raffaella Clerici^c ; Mario Guidotti^c ; Paola Banfi^d ; Giorgio Bono^d ; Franca Marino^a
• 关键词：Clinically isolated syndrome ; Multiple sclerosis ; mRNA levels ; Dopaminergic receptors ; Adrenoceptors ; Peripheral blood mononuclear cells ; CD4+ T effector lymphocytes ; CD4+ T regulatory lymphocytes
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：9
• 期：Complete
• 页码：376-381
• 全文大小：196 K
• 卷排序：9

文摘

This data article presents a dataset of mRNA levels for dopaminergic receptors, adrenoceptors and for tyrosine hydoxylase, the rate-limiting enzyme in the synthesis of catecholamines, in peripheral blood mononuclear cells as well as in CD4+ T effector and regulatory cells from subjects with clinically isolated syndromes (CIS), which is a first episode of neurological disturbance(s) suggestive of multiple sclerosis. CIS subjects are divided into two groups according to their eventual progression, after 12 months from CIS, to clinically established multiple sclerosis. The data reported are related to the article entitled "Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis" (M. Cosentino, M. Zaffaroni, M. Legnaro, R. Bombelli, L. Schembri, D. Baroncini, A. Bianchi, R. Clerici, M. Guidotti, P. Banfi, G. Bono, F. Marino, 2016) [1].