Venoms of juvenile and adult Naja kaouthia were analyzed for ontogenetic variation.

Hypothesized taxon-specific toxicity of nonconventional 3FTxs was not observed.

Venom PLA₂ activity was significantly lower, with fewer isoforms, in juvenile venom.

Alpha-cobratoxin was the only peptide highly toxic toward both lizards and mice.

This venom compositional strategy allows snakes to immobilize diverse prey rapidly.