Pregnancy as a risk factor for severe outcomes from influenza virus infection: A systematic review and meta-analysis of observational studies

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• 作者：Dominik Mertz^a ; ^b ; ^c ; ^d ; Johanna Geraci^e ; Judi Winkup^b ; Bradford D. Gessner^f ; Justin R. Ortiz^g ; Mark Loeb^b ; ^c ; ^d ; ^{loebm@mcmaster.ca}
• 关键词：CI ; confidence interval ; CENTRAL ; Cochrane Central Register of Controlled Trials ; ICU ; intensive care units ; NOS ; Newcastle Ottawa Scale ; OR ; odds ratio ; RR ; risk ratio ; WHO ; World Health Organization
• 刊名：Vaccine
• 出版年：2017
• 出版时间：23 January 2017
• 年：2017
• 卷：35
• 期：4
• 页码：521-528
• 全文大小：1428 K
• 卷排序：35

文摘

Pregnancy is considered an important risk factor for severe outcomes from influenza virus infection. The World Health Organization recommends that pregnant women be prioritized for vaccination. No comprehensive systematic review supporting this recommendation has been conducted to date. We found a higher risk for hospital admission following influenza but found no increase in mortality or other outcomes. Comparative, population-based studies are needed to best evaluate the attributable risk of pregnancy.