All Ca2 +-binding loops of light-sensitive ctenophore photoprotein berovin bind magnesium ions: The spatial structure of Mg2 +-loaded apo-berovin
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- 作者：Ludmila P. Burakovaa ; b ; c ; 1 ; Pavel V. Natashina ; b ; c ; 1 ; Natalia P. Malikovab ; Fengfeng Niuc ; d ; Mengchen Puc ; Eugene S. Vysotskib ; eugene.vysotski@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Zhi-Jie Liua ; c ; d ; liuzhj@shanghaitech.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bioluminescence ; Coelenterazine ; Aequorin ; Obelin ; Calcium
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：154
- 期：Complete
- 页码：57-66
- 全文大小：1453 K
文摘
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The spatial structure of apo-berovin with bound Mg2 + is determined at 1.75 Å.
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Magnesium ions are found in each functional EF-hand loop of a photoprotein.
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Mg2 + is coordinated by oxygen atoms with characteristic oxygen-Mg2 + distances.
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These findings account for the influence of Mg2 + on berovin bioluminescence.