Regional volumetric change in Parkinson's disease with cognitive decline

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• 作者：Myrlene Gee^a ; Juergen Dukart^b ; ^c ; Bogdan Draganski^c ; WR Wayne Martin^d ; Derek Emery^a ; ^e ; Richard Camicioli^d ; ^{rcamicio@ualberta.ca}
• 关键词：Magnetic resonance imaging ; Statistical parametric mapping ; Parkinson's disease ; Cognitive decline ; Dementia
• 刊名：Journal of the Neurological Sciences
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：373
• 期：Complete
• 页码：88-94
• 全文大小：1063 K
• 卷排序：373

文摘

Brain MRI changes occur in patients with Parkinson's disease who develop significant cognitive decline or dementia. Changes can measured using statistical parametric mapping. Longitudinal cluster changes occur in the right insula and bilateral hippocampi and right cuneus. MRI changes can be used to track meaningful cognitive decline in Parkinson's disease.