Identification and anti-tumour activities of phenolic compounds isolated from defatted adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) seed meal
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- 作者：Chao Chena ; b ; c ; Yiyi Zhanga ; b ; c ; Yulong Gaoa ; b ; c ; Qian Xua ; b ; c ; Xingrong Jua ; b ; c ; Lifeng Wanga ; b ; c ; wanglifeng_8@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Defatted adlay seed meal ; Phenolic compounds ; Anti-tumour activity ; N1 ; N5-di-[(E)-p-coumaroyl]-spermidine ; Western blot analysis
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：26
- 期：Complete
- 页码：394-405
- 全文大小：1543 K
文摘
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A bioassay-guided isolation was used to identify anti-tumour constituents in defatted adlay seed meal.
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Four phenolic compounds were isolated and identified from defatted adlay seed meal.
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N1,N5-Di-[(E)-p-coumaroyl]-spermidine showed the highest anti-tumour activity.
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Levels of the anti-apoptotic and apoptotic proteins in HepG2 cells treated with compound 1 were detected.