Current status of fluid biomarkers in mild traumatic brain injury
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- 作者：Jacqueline R. Kulbe ; James W. Geddes ; jgeddes@uky.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：AHI ; Abusive Head Injury ; AUC ; Area Under The Curve ; BCAA ; Branched Chain Amino Acids ; CCI ; Controlled Cortical Impact ; CCR5 ; Chemokine Receptor 5 ; CRMP ; Collapsin Response Mediator Protein Family ; CTE ; Chronic Traumatic Encephalopathy ; GCS ; Glasgow Coma Scale ; GFAP ; Glial Fibrillary Acidic Protein ; GFAP-BDP ; Glial Fibrillary Acidic Protein Breakdown Product ; FPR1 ; Formyl Peptide Receptor 1 ; GAP43 ; Growth Associated Protein 43 ; GOSE ; Glasgow Outcome Scale Extended ; HGF ; Hepatocyte Growth Factor
- 刊名：Experimental Neurology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：275
- 期：part_P3
- 页码：334-352
- 全文大小：452 K
文摘
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Biomarkers of mild traumatic brain injury would aid in diagnosis, prognosis, return to play/duty assessments, and further elucidate pathophysiology.
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The majority of biomarker research focuses on moderate to severe injury or uses a hypothesis-driven approach.
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Summary of potential serum and cerebral spinal fluid biomarkers of mild traumatic brain injury.
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Innovative and unbiased methods of discovery should be utilized in order to discover novel biomarkers of mild traumatic brain injury.