Palladium-Catalyzed Stille Couplings of Aryl-, Vinyl-, and Alkyltrichlorostannanes in Aqueous Solution

详细信息    查看全文

• 作者：Rai ; Roopa ; Aubrecht ; Katherine B. ; Collum ; David B.
• 刊名：Tetrahedron Letters
• 出版年：1995
• 出版时间：May 1, 1995
• 年：1995
• 卷：36
• 期：18
• 页码：3111-3114
• 全文大小：186 K

文摘

Stille coupling of water-soluble aryl and vinyl halides with alkyl-, aryl-, and vinyltrichlorostannane derivatives (RSnClb>3b>) are effected in aqueous solution using a catalyst generated in situ from PdClb>2b> and KOH both with and without added PhP(m-Cb>6b>Hb>4b>SOb>3b>Na)b>2b>. The yields are generally good to excellent, although some limitations of the protocol are described.