Degree of obesity influences the relationship of PAI-1 with body fat distribution and metabolic variables in African women
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- 作者：Sunelle A. Barnard 13024787@nwu.ac.za" class="auth_mail" title="E-mail the corresponding author ; Marlien Pieters ; marlien.pieters@nwu.ac.za" class="auth_mail" title="E-mail the corresponding author ; Cornelie Nienaber-Rousseau cornelie.nienaber@nwu.ac.za" class="auth_mail" title="E-mail the corresponding author ; Herculina S. Kruger salome.kruger@nwu.ac.za" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANCOVA ; analysis of co-variance ; ANOVA ; analysis of variance ; ASM ; appendicular skeletal muscle mass ; BMI ; body mass index ; CI ; confidence interval ; CRP ; C-reactive protein ; DXA ; dual-energy x-ray absorptiometry ; ECLIA ; electrochemiluminescence immunoassay ; FNIH ; Foundation for the National Institutes of Health ; HIV ; human immunodeficiency virus ; HREC ; Health Research Ethics Committee ; HOMA-IR ; homeostatic model assessment of insulin resistance ; IR ; insulin resistance ; ISAK ; International Societ
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：95-102
- 全文大小：313 K
文摘
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The association of PAI-1 with body fat distribution in Africans is unclear.
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PAI-1 did not differ between SO and non-sarcopenic obese women.
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Fat distribution and degree of obesity influenced the association of PAI-1 with metabolic co-variates.
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Abdominal SCAT is an important contributor to plasma PAI-1 in centrally obese women.
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Body fat % did not contribute significantly to PAI-1 variance in obese African women.