Effect of cyto/chemokine degradation in effective intercellular communication distances

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• 作者：V.K. Gupta ; ^{vkg@engr.colostate.edu}
• 关键词：Cell motility ; Cell signaling ; Intercellular communication ; Cyto/chemokine degradation ; Communication distance
• 刊名：Physica A: Statistical Mechanics and its Applications
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：468
• 期：Complete
• 页码：244-251
• 全文大小：703 K
• 卷排序：468

文摘

We examine the effect of degradation of secreted molecules on the effective communication distance. We demonstrate that in presence of degradation the effective communication distances are significantly reduced. The reduction in effective communication distance is dependent on the degradation rate. Higher the degradation rate, lower the effective intercellular communication distance.