Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease
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- 作者：Matthew R. Kudek1 ; kudek011@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Ryan Shanley2 ; Nicole D. Zantek3 ; David H. McKenna3 ; Angela R. Smith4 ; Weston P. Miller4
- 关键词：Umbilical cord blood transplant ; Nonmalignant disorders ; Alternative donor transplant ; Graft&ndash ; recipient ABO compatibility
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：22
- 期：11
- 页码：2019-2024
- 全文大小：626 K
文摘
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UCB–recipient ABO compatibility was analyzed in a nonmalignant UCBT population.
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Two hundred seventy patients, mostly pediatric, with various primary diagnoses were studied.
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ABO compatibility does not impact post-transplant RBC transfusion burden.
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Graft failure, donor chimerism, GVHD, and other UCBT outcomes were also unaffected.
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ABO compatibility should not be a major criterion for UCB selection for NMD.