Mitochondria and mitochondrial DNA in porcine oocytes and cumulus cells ‿A search for developmental competence marker
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- 作者：Piotr Pawlak ; piotr.pawlak@up.poznan.pl" class="auth_mail" title="E-mail the corresponding author ; Agnieszka Chabowska ; Natalia Malyszka ; Dorota Lechniak
- 关键词：Oocyte ; Cumulus ; mtDNA ; Mitochondria ; Puberty ; Developmental competence ; Quality
- 刊名：Mitochondrion
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：27
- 期：Complete
- 页码：48-55
- 全文大小：864 K
文摘
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Growth environment (follicular fluid and cumulus cells) significantly influence the developmental competence of oocytes
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The prepubertal and cyclic gilts differ significantly in terms of oocyte and embryo developmental competence
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MtDNA copy number in cumulus cells correlate with mtDNA copy number in individual oocytes before in vitro maturation
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Puberty does not influence the mtDNA copy number and mitochondria distribution in oocytes
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Every fourth oocyte is useless for IVF due to mtDNA copy number which is too low to support early embryonic development