Novosphingobium resinovorum SA was the first single isolate capable of utilizing sulfanilic acid as sole carbon nitrogen and sulfur source. The bacterium can also grow on several other substituted aromatic compounds. The complete and annotated genome of the strain is presented. Besides the chromosome, the isolate has four extrachromosomal elements of various sizes. The genes encoding proteins involved in the catabolism of sulfanilic acid and other aromatics are reported.