Diagnostic and prognostic accuracy of galectin-3 and soluble ST2 for acute heart failure

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• 作者：Thomas Mueller^a ; ^{thomas.mueller@bs-lab.at} ; Alfons Gegenhuber^b ; Isabella Leitner^a ; Werner Poelz^c ; Meinhard Haltmayer^a ; Benjamin Dieplinger^a
• 关键词：AUC ; area under the curve ; BNP ; B-type natriuretic peptide ; CI ; confidence interval ; CV ; coefficient of variation ; eGFR ; estimated glomerular filtration rate ; FDA ; food and drug administration ; HF ; heart failure ; HFpEF ; heart failure with preserved ejection fraction ; HFrEF ; heart failure with reduced ejection fraction ; LVEF ; left ventricular ejection fraction ; NT-proBNP ; amino terminal pro-B-type natriuretic peptide ; ROC curve ; receiver operating characteristic curve ; sST2 ; soluble isoform of th
• 刊名：Clinica Chimica Acta
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：463
• 期：Complete
• 页码：158-164
• 全文大小：512 K
• 卷排序：463

文摘

We compared diagnostic and prognostic values of galectin-3, sST2 and BNP for heart failure. Patients with dyspnoea were studied in an emergency setting. In contrast to BNP, galectin-3 and sST2 were not useful as an aid in the diagnosis of heart failure. Galectin-3, sST2 and BNP were equally useful for the prediction of mortality in heart failure patients. Galectin-3 and sST2 did not add to the diagnostic and prognostic value of BNP.