Testing conditions in shock-based contextual fear conditioning influence both the behavioral responses and the activation of circuits potentially involved in contextual avoidance
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- 作者：Juliette Viellarda ; Marcus Vinicius C. Baldob ; Newton Sabino Canterasa ; newton@icb.usp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Contextual fear conditioning ; Non-instrumental avoidance ; Risk assessment ; Hypothalamus ; Periaqueductal gray
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：315
- 期：Complete
- 页码：123-129
- 全文大小：1067 K
文摘
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Animals confined to the conditioning chamber or with free access to the conditioning chamber were tested using shock-based fear conditioning.
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Different testing conditions yielded different contextual responses and engaged different circuits related to aversive responses.
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Animals with free access to the conditioning chamber displayed risk assessment responses and engage a distinct hypothalamic – PAG circuit.