An assessment of sex differences in Δ⁹-tetrahydrocannabinol (THC) taste and place conditioning

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• 作者：Briana J. Hempel ; ^{bg0767a@student.american.edu} ; Alison G.P. Wakeford ; Katharine H. Nelson ; Matthew M. Clasen ; Claudia J. Woloshchuk ; Anthony L. Riley ^{alriley@american.edu}
• 刊名：Pharmacology Biochemistry and Behavior
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：153
• 期：Complete
• 页码：69-75
• 全文大小：423 K
• 卷排序：153

文摘

THC failed to induce place preferences or aversions at 0.15, 1 or 6 mg/kg. This failure was evident in both males and females. THC conditioned dose-dependent taste avoidance. Females were more sensitive to THC's aversive properties than were males. The place conditioning design is likely an insensitive index of THC's affective properties.