• 作者：M. Vá ; zquez Rodrí ; guez ; ^{mvazrod8@yahoo.es} ; R. Vidal Herná ; ndez ; I. Pardo Pumar ; S. Campos Arca ; A. Otero Valenzuela
• 关键词：Conizaci&oacute ; n cervical ; Lesi&oacute ; n intraepitelial cervical ; HPV ; Seguimiento posconizaci&oacute ; n ; Persistencia ; Recurrencia
• 刊名：Cl¨ªnica e Investigaci¨®n en Ginecolog¨ªa y Obstetricia
• 出版年：2009
• 出版时间：July-August 2009
• 年：2009
• 卷：36
• 期：4
• 页码：144-147
• 全文大小：311 K

Objectives

To evaluate conization as a treatment of cervical intraepithelial neoplasm (CIN), as well as complications and subsequent follow-up.

Material and methods

A retrospective study was performed in 79 patients with distinct grades of CIN treated with conization from 1st January 2004 to 31st December, 2006. Follow-up visits were made at 6 and 12 months.

Results

The mean age of the patients was 37.7 years and the most common indication was high-grade squamous intraepithelial lesion (H-SIL). Conization was performed by diathermy loop in 49.36 % , electrosurgical needle in 35.44 % and cold-knife in 15.19 % . Human papilloma virus (HPV)-DNA determination was positive in 72 patients. Postoperative bleeding occurred in five patients. Histopathological analysis of the cone revealed H-SIL in 86 % , with free margins in 88.3 % . At 1 year after conization, persistent disease was found in three patients.

Conclusions

Cervical conization as a means of excising CIN is a simple and effective technique with few complications that allows correct histopathological analysis of the surgical specimen.