DABCO-mediated aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to cycloalkenones. Regioselective synthesis of disubstituted 1,2,3-triazoles
文摘
Metal-free synthesis of disubstituted triazoles through aza-Michael reaction. A novel DABCO-promoted synthesis of disubstituted 1,2,3-triazoles is unraveled. Disubstituted 1,2,3-triazoles were obtained in excellent combined yields. The EWGs and ERGs on aryl moiety of Michael donor could tolerate the reaction.