Studies on physico-chemical and antibacterial properties of grafted pullulans solutions

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• 作者：Anca Giorgiana Grigoras ; Marieta Constantin ; Vasile Cristian Grigoras ; Simona Isabela Dunca ; Lacramioara Ochiuz
• 关键词：Pullulan-g-poly(3-acrylamidopropyl)trimethylammonium chloride ; Salt ; Static light scattering ; Antibacterial activity
• 刊名：Reactive and Functional Polymers
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：73
• 期：9
• 页码：1249-1254
• 全文大小：992 K

文摘

The physico-chemical properties of three grafted pullulans (P) having linked poly(3-acrylamidopropyl)trimethylammonium chloride (pAPTAC) as side chains (P-g-pAPTAC1, P-g-pAPTAC2 and P-g-pAPTAC3 with 22.53, 29.05, and 34.51 (wt. % ) of pAPTAC content in polymer, respectively) and possessing polyelectrolyte character were determined by light scattering analysis. All grafted pullulan aqueous solutions were tested in the presence of 0.5 M NaCl, KCl, NaNO₃ or KNO₃. The biggest associations were recorded in 0.5 M NaCl aqueous solutions for P-g-pAPTAC1, P-g-pAPTAC2 and P-g-pAPTAC3 according to the maximum values for R_g extracted from MALLS (multiangle laser light scattering) measurements. Also, the dominant conformation in salted solution of these polyelectrolytes was random coil as Debye plot analysis revealed. Antibacterial activity was tested by Kirby-Bauer diffusion method and all grafted pullulans dissolved in aqueous solutions of 0.5 M NaCl have developed inhibition zone against Staphylococcus aureus (ATCC 25923).