Improvements in life expectancy in adult type 2 diabetes patients in the last six decades

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• 作者：Sorin Ioacara^a ; ^{drsorin@yahoo.com"" rel=""nofollow} ; Cristian Guja^a ; Constantin Ionescu-Tirgoviste^a ; Simona Fica^b ; Sorin Sabau^c ; Stefania Radu^a ; Andrei Micu^a ; Cristina Tiu^d
• 关键词：Survival ; Age at onset ; Age at death ; Disease duration ; Causes of death
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2011
• 出版时间：June 2011
• 年：2011
• 卷：92
• 期：3
• 页码：400-404
• 全文大小：244 K

文摘

Summary

Aim

To investigate the historical changes in survival with diabetes in adult type 2 diabetes patients.

Methods

We analyzed 9066 deaths, 54.2 % males, registered at “I. Pavel” Bucharest Diabetes Centre, aged 40–64 years and deceased between 1943 and 2009. We split the analysis in three time periods according to year of death: 1943–1965, 1966–1988 and 1989–2009.

Results

The mean age at diabetes onset was 55.5 ± 6.2 years, with mean disease duration at death 12.7 ± 8.2 years and mean age at death 68.2 ± 8.7 years. The mean disease duration at death was 9.9 ± 7.3 years in 1943–1965 period, followed by a significant (p < 0.001) rise to 12.2 ± 8.2 years in 1966–1988, and 14 ± 8.1 years (p < 0.001) in 1989–2009. There was a significant increase for coronary heart diseases and cancer and a significant decrease for infections and end-stage renal disease as causes of death.

Conclusion

We found a significant increase in age at onset and survival with diabetes leading to a significant increase in age at death.