Four haptens —clioquinol, thimerosal, mercury, and primin—have been eliminated owing to a low frequency of relevant allergic reactions, while 3 new allergens —methylisothiazolinone, diazolidinyl urea, and imidazolidinyl urea—have been added. GEIDAC has also modified the recommended aqueous solution concentrations for the 2 classic, major haptens methylchloroisothiazolinone/methylisothiazolinone mix, which is now to be tested at 200 ppm in aqueous solution, and formaldehyde, which is now to be tested in a 2% aqueous solution.
Updating the Spanish standard series is one of the functions of GEIDAC, which is responsible for ensuring that the standard series is suited to the country's epidemiological profile and pattern of contact sensitization.