The kynurenine pathway and the brain: Challenges, controversies and promises

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• 作者：Robert Schwarcz^a ; ^{rschwarc@mprc.umaryland.edu} ; Trevor W. Stone^b
• 关键词：3-Hydroxykynurenine ; Kynurenic acid ; Neuroimmunology ; Neurology ; Psychiatry ; Quinolinic acid
• 刊名：Neuropharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：112
• 期：part_PB
• 页码：237-247
• 全文大小：578 K
• 卷排序：112

文摘

The kynurenine pathway controls several neurotransmitters directly and indirectly. Kynurenines may be involved in the etiology of psychiatric and neurological disorders. Targeting the kynurenine pathway with new specific agents may prevent disease.