Tropomyosin and Profilin Cooperate to Promote Formin-Mediated Actin Nucleation and Drive Yeast Actin Cable Assembly

详细信息    查看全文

• 作者：Salvatore L. Alioto¹ ; Mikael V. Garabedian¹ ; Danielle R. Bellavance¹ ; Bruce L. Goode¹ ; ² ; ^{goode@brandeis.edu}
• 关键词：actin ; profilin ; formin ; tropomyosin ; yeast
• 刊名：Current Biology
• 出版年：2016
• 出版时间：5 December 2016
• 年：2016
• 卷：26
• 期：23
• 页码：3230-3237
• 全文大小：3721 K
• 卷排序：26

文摘

tpm1Δ diminishes actin cables and polarized secretion in bnr1Δ, but not bni1Δ, cells Tpm1 works with profilin to promote Bni1-mediated actin filament nucleation Tpm1 has no effects on Bnr1, and Tpm2 has no effects on either Bni1 or Bnr1