Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis
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- 作者：Andreas H. Laustsena ; José ; Marí ; a Gutié ; rrezb ; Arne R. Rasmussenc ; Mikael Engmarkd ; Peter Gravlunde ; Kate L. Sandersf ; Brian Lohsea ; Bruno Lomonteb ; bruno.lomonte@ucr.ac.cr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aipysurus laevis ; Olive sea snake ; Snake venom ; Proteomics ; Toxicity ; Venomics
- 刊名：Toxicon
- 出版年：2015
- 出版时间：1 December 2015
- 年：2015
- 卷：107
- 期：part_PB
- 页码：187-196
- 全文大小：1857 K
文摘
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The venom proteome of the olive sea snake, Aipysurus laevis, is presented.
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Most abundant venom components are phospholipases A2 and short neurotoxins.
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Lethality screening coupled to abundance estimation identified the medically relevant toxins.
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BioCSL Sea Snake Antivenom neutralizes venom lethality.
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ICP Anti-Coral Antivenom cross-recognizes phospholipases A2 from A. laevis venom.