Genus Calliophis of Asiatic coral snakes: A deficiency of venom cross-reactivity and neutralization against seven regional elapid antivenoms
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- 作者：Choo Hock Tana ; tanch@um.edu.my" class="auth_mail" title="E-mail the corresponding author ; tanchoohock@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jia Lee Liewa ; Kae Yi Tanb ; Nget Hong Tanb
- 关键词：Calliophis bivirgata ; Calliophis intestinalis ; ELISA ; Antigen binding ; Antivenom ; Cross-neutralization
- 刊名：Toxicon
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：130-133
- 全文大小：487 K
文摘
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Venoms of Calliophis bivirgata and Calliophis intestinalis were studied.
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Methods included indirect ELISA and lethality neutralization in mice.
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Both venoms showed negligible cross-immunoreactivity against elapid antivenoms.
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C. bivirgata venom lethality in mice was not cross-neutralized by the antivenoms.
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There is implication on the production of a pan-regional poly-specific antivenom.